MacArthur Fellows Program

Arnold J. Mandell

Neuroscientist and Psychiatrist | Class of March 1984

Neuroscientist and Psychiatrist
La Jolla, California
50 at time of award
Published March 1, 1984

About Arnold's Work

Arnold Mandell uses the mathematics of nonlinear systems and statistical mechanics to investigate neurobiological problems with implications for brain-related disorders.

In contrast to current trends in medical research which focus on genetic molecular disorders, Mandell’s work seeks to demonstrate that normal molecular mechanisms can and do become organized in pathological ways, in time and space, to result in dysfunction.  He refers to these dysfunctions as “dynamical disorders.”  His studies range from those involving brain enzymes and transmembrane receptors to neurobiological mechanisms of behavior.


Mandell is vice-president of research at the Cielo Institute in Asheville, North Carolina.  He also serves as research professor in the Department of Psychiatry and Behavioral Science at the Emory University School of Medicine, research professor of mathematical sciences at Florida Atlantic University, and professor emeritus of psychiatry at the University of California, San Diego Medical School, where he was founding chairman of the Department of Psychiatry (1968).  He has published two nonfiction novels, The Nightmare Season (1976) and Coming of (Middle) Age, A Journey (1978), in addition to the book, The Nearness of Grace (2005).

Mandell received a B.A. (1954) from Stanford University and an M.D. (1958) from Tulane University.

Last updated January 1, 2005.

Select News Coverage of Arnold J. Mandell
January 25, 2018
“Arnold Mandell by David Healy”
American College of Neuropsychopharmacology
Arnold J. Mandell , 1984 MacArthur Fellow
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